Oxford
Oxford
Birmingham
Birmingham
Driving

Oxford to Birmingham

Updated: 30 May 2026

The drive from Oxford to Birmingham covers approximately 250 kilometers and takes about 2.5 hours. You will travel east on MS-6 to I-22 E, which leads directly into Birmingham. This route is efficient and passes through the scenic landscapes of North Mississippi and Alabama. It is a common route for those traveling for business or leisure.

Total Distance: Driving distance 250 km, straight-line air distance 210 km.
Fastest Way
Driving via I-22 E is the fastest route.
Cheapest Way
Driving your own vehicle is the most practical and cheapest option.
Compare Oxford to Birmingham Routes
Driving
Direct
Duration
2 hours 30 mins
Avg Price
$30 - $45 in fuel
Operator
Personal Vehicle
Route
MS-6 E to I-22 E

I-22 is a well-maintained interstate connecting the two regions.

Travel Tips
  • Route Choice
    I-22 E is the most efficient highway; follow signs for Birmingham.
  • Traffic
    Birmingham traffic can be heavy; check maps before entering the city.
  • Rest Stops
    There are many stops along I-22.
  • Planning
    Check for road construction updates on state transportation websites.
  • Timing
    Try to arrive in Birmingham outside of peak rush hours.
Safety Tips
  • Speeding
    Police monitor speed limits on I-22; stay within limits.
  • Night Driving
    Be cautious of wildlife on rural sections of the highway.
  • Vehicle Prep
    Ensure your vehicle is in good condition for a 2.5-hour drive.
  • Emergency
    Keep a mobile phone charged and have a roadside assistance plan.
People Also Ask
  • How long is the drive to Birmingham?
    It takes about 2.5 hours to drive from Oxford to Birmingham.
  • Is there a train to Birmingham?
    No, there is no passenger rail service between Oxford and Birmingham.
  • What is the best route?
    Taking I-22 E is the most direct route.
  • Are there tolls?
    No, there are no toll roads on this route.
  • Is it a safe drive?
    Yes, it is a standard, safe highway drive.
Quick Info
  • From Oxford, Mississippi, United States
  • To Birmingham, Alabama, United States
  • Modes
Best Time to Travel

Spring or Fall for comfortable weather in Birmingham.

Things to Do in Birmingham
1
Birmingham Civil Rights Institute
A significant museum documenting the history of the Civil Rights Movement in Birmingham.
2
Barber Vintage Motorsports Museum
A world-class museum featuring a massive collection of vintage motorcycles and cars.
3
Railroad Park
A beautiful urban park in the heart of downtown Birmingham, perfect for walking and relaxing.
4
Vulcan Park and Museum
Home to the world's largest cast-iron statue, offering panoramic views of the city.
Tags
Oxford to Birmingham drive I-22 E route Birmingham travel guide driving distance Oxford to Birmingham Alabama travel Oxford MS to Birmingham AL best way to travel to Birmingham Birmingham attractions