The drive from Paducah to Miami is approximately 1,600 kilometers. You will travel south through Nashville, Atlanta, and down the entire length of Florida via I-75 and the Florida Turnpike. This is a very long journey that takes about 17 hours. Driving is the most practical mode of transport as air travel would require multiple connections.
Total Distance: 1,600 km driving, 1,400 km air distance.
This is a multi-day drive; plan for an overnight stop.
Winter or spring to avoid the intense summer heat and hurricane season.