The journey from Palmetto to Jacksonville is approximately 380 kilometers, taking about 4 hours via I-75 North and I-10 East. This route traverses the center of the state before heading northeast. Jacksonville is a sprawling city with a rich history and access to the Atlantic Ocean. Ensure you plan for potential traffic delays around the Orlando and Gainesville areas. It is a long drive, so schedule regular stops to stay refreshed.
Total Distance: 380 km driving distance, 340 km straight-line air distance.
The I-75/I-10 interchange is a major junction; follow signs for Jacksonville.
Spring or Fall, when the weather is comfortable for exploring the city's parks.