Driving
Panama City to Memphis
Updated: 28 May 2026
The drive from Panama City to Memphis is approximately 500 miles. You will take US-231 North to I-22 West to reach this major city. The trip typically takes 8 hours, depending on traffic. This route is well-traveled and offers many amenities along the way. It is a common route for those commuting or visiting the northern part of the state.
Total Distance: 805 km driving distance; 720 km straight-line air distance.
Fastest Way
Driving via US-231 and I-22 is the fastest route, taking 8 hours.
Cheapest Way
Driving your own vehicle is the most cost-effective method, costing about $110 in fuel.
Compare Panama City to Memphis Routes
Driving
Direct
Duration
8 hours
Avg Price
$100-$120 in fuel
Operator
Personal Vehicle
Route
US-231 North to I-22 West.
Expect traffic near the Memphis city limits.
Travel Tips
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Traffic PlanningAvoid the Memphis city center during rush hour.
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NavigationUse GPS to navigate the local roads in Memphis.
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Vehicle PrepCheck your tire pressure before the drive.
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Rest StopsThere are many gas stations along US-231.
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Departure TimeAny time is generally fine for this drive.
Safety Tips
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Aggressive DrivingTraffic on I-22 can be fast-paced; stay alert.
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Weather AwarenessBe prepared for sudden afternoon thunderstorms.
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Emergency KitKeep a basic roadside kit in your vehicle.
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Personal SafetyStay aware of your surroundings when parking in busy areas.
People Also Ask
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Is there a train?No, there is no direct passenger train service between Panama City and Memphis.
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How long is the drive?The drive is approximately 8 hours.
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Are there tolls?No, this route is generally toll-free.
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Is it a safe drive?Yes, it is a standard highway route.
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What is the best time to leave?Any time is fine for this drive.
Quick Info
- From Panama City, Florida, United States
- To Memphis, Tennessee, United States
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Modes
Best Time to Travel
Year-round, as the drive is moderate and weather is generally consistent.
Things to Do in Memphis
1
Graceland
Visit the home of Elvis Presley. It is a must-see for tourists.
2
Sun Studio
See the historic studio. It is a popular spot for tourists.
3
National Civil Rights Museum
Learn about the history of the civil rights movement. It is a must-see for history buffs.
4
Beale Street
Enjoy the music and nightlife. It is a great place for families.
Tags
Panama City to Memphis
driving route Tennessee
US-231
travel time Panama City to Memphis
Florida to Tennessee road trip
Memphis travel
best way to get to Memphis
highway guide
