The drive from Panama City to Sarasota is approximately 600 kilometers and takes about 7 hours. The most direct route is via US-98 East to I-75 South. Sarasota is a beautiful coastal city known for its stunning beaches and cultural attractions, and is best explored by car. Be prepared for varying road conditions as you travel through rural areas and into the coastal region.
Total Distance: 600 km driving distance; 500 km straight-line air distance.
Check for traffic updates on I-75, as it can get congested near Sarasota.
Spring or autumn for pleasant weather and to avoid the peak summer heat.