The trip from Pleasanton to Daly City is a 40-mile journey west across the Bay Area. You will primarily use I-580 West to I-280 North. Expect a travel time of 55 to 80 minutes depending on traffic. This route is a common commute for residents in the Tri-Valley area working in the San Francisco area.
Total Distance: 65 km driving distance, 50 km air distance.
The Bay Bridge has a toll; use a FasTrak transponder for convenience.
Any time, though avoid peak morning and evening commute hours.