The journey from Plymouth to Tampa spans approximately 1,500 miles. Most travelers prefer flying from Minneapolis-St. Paul International Airport to Tampa International Airport. Driving requires navigating I-35 South through Iowa and Missouri before connecting to I-75. The drive takes roughly 24 hours of pure transit time. You will cross diverse landscapes from the Midwest plains to the humid Florida coast. Plan for significant traffic near Atlanta if driving.
Total Distance: 2,400 km driving, 2,100 km air.
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Direct
|
Direct
|
|
|---|---|---|
| Duration | 3 hours 15 mins | 24 hours |
| Avg Price | $150-$400 | $300-$500 in fuel |
| Operator | Delta Air Lines | Personal Vehicle |
| Route | MSP to TPA | I-35 S to I-24 E to I-75 S |
| Tip | Book at least 3 weeks in advance for the lowest fares. | Stop in Nashville to break up the long drive. |
November to April for mild weather and avoiding hurricane season.