Is Des Moines a good place to visit?

Yes, it is known for its vibrant arts scene and friendly atmosphere.

How far is Des Moines from Chicago?

It is approximately a 5-hour drive from Chicago.

Are there direct flights?

No, you will need at least one connection from Salisbury.

What is the best route by car?

I-70 to I-80 is the most direct and well-maintained route.

Is it safe to drive alone?

Yes, provided you stick to major interstates and plan your stops.

Pocomoke City

Des Moines

Flight Driving

Pocomoke City to Des Moines

Updated: 30 May 2026

The journey from Pocomoke City to Des Moines spans roughly 1,800 km. You can fly from Salisbury (SBY) to Des Moines International Airport (DSM) with a connection, usually in Chicago or Charlotte. Driving takes about 19 hours via I-70 W and I-80 W. This route takes you through the heart of the American Midwest, passing through cities like Columbus and Indianapolis. It is a scenic drive that showcases the transition from coastal plains to rolling farmland.

Total Distance: 1,800 km driving distance; 1,600 km straight-line air distance.

Fastest Way

Flying is the fastest method, saving over 12 hours compared to driving.

Cheapest Way

Driving is the most economical choice for groups or families.

Compare Pocomoke City to Des Moines Routes

	Flight Connecting	Driving Direct
Duration	6 hours 30 mins	19 hours
Avg Price	$400 - $650	$280 - $400 in fuel
Operator	United Airlines	Personal Vehicle
Route	SBY to ORD to DSM	US-13 N to I-70 W to I-80 W
Tip	Check baggage policies as regional flights often have stricter weight limits.	Use cruise control on the flat stretches of I-80 to improve fuel efficiency.

Travel Tips

Airport Parking
Use long-term parking at SBY to save on daily rates.
Midwest Driving
Be prepared for sudden wind gusts when driving through open Iowa farmland.
Dining
Stop in Indianapolis for a wide variety of food options midway through the drive.
Navigation
Download offline maps as cell service can be spotty in rural parts of the Midwest.
Booking
Use flight comparison tools to find the best connection times through Chicago O'Hare.

Safety Tips

Night Driving
Avoid driving late at night on rural highways to prevent wildlife collisions.
Tire Safety
Check your tire pressure before leaving, as highway speeds increase heat buildup.
Resting
Take a 15-minute break every two hours to stay sharp.
Communication
Share your itinerary with a family member before departing.