The drive from Pocomoke City to Pittsburgh covers approximately 350 miles. You will travel west through Maryland and into Pennsylvania. The journey typically takes 6 hours. This route takes you through the scenic Appalachian Mountains.
Total Distance: 560 km driving distance; 450 km straight-line air distance.
Expect heavy traffic near Pittsburgh, especially on the I-376 corridor.
Spring and Fall are the most pleasant times to visit Pittsburgh.