The drive from Ponca City to Phoenix is approximately 1,200 miles southwest. You will take US-60 to I-40 west across the Texas Panhandle and New Mexico, then I-17 south to Phoenix. This is a very long drive. Expect a significant change in landscape from plains to desert.
Total Distance: Driving distance 1,900 km; Air distance 1,600 km.
The drive through New Mexico is scenic.
Fall or Spring to avoid the extreme summer heat.