The journey from Port Orange to Charleston spans approximately 450 miles along the Atlantic coast. Most travelers prefer driving via I-95 North, which takes about 7 hours depending on traffic in Jacksonville and Savannah. You will pass through the scenic Lowcountry region as you approach South Carolina. This route is popular for its accessibility and the ability to stop in historic cities along the way. It is a straightforward drive that avoids major mountain passes.
Total Distance: 725 km driving distance; 600 km straight-line air distance.
Avoid rush hour traffic in Jacksonville to save 45 minutes.
Spring months of March through May offer mild temperatures and blooming azaleas.