The trip from Portland, Maine to San Diego, California is a long-distance journey across the country. The most practical mode is a connecting flight from Portland International Jetport (PWM) to San Diego International Airport (SAN). You will typically connect through hubs like Philadelphia, Charlotte, or Dallas. Total travel time is usually between 9 and 12 hours. You will transition from the rocky Atlantic coast to the sunny Pacific coast.
Total Distance: Driving distance 4,900 km, straight-line air distance 4,200 km.
American Airlines provides frequent connections through their East Coast hubs.
March through May and September through November offer the most pleasant temperatures.