The drive from Prineville to Spokane is a 380-mile journey through the scenic landscapes of Eastern Oregon and Washington. You will primarily follow US-97 North to US-395 North. This route takes you through the Columbia River Gorge and the rolling hills of the Palouse. The journey typically takes 7 to 8 hours of driving time. It is a beautiful drive that showcases the diverse geography of the Pacific Northwest.
Total Distance: 610 km driving distance; 480 km straight-line air distance.
Stop in the Columbia River Gorge for a scenic break.
Spring or autumn for the best weather and scenery.