Is there a train to Lexington?

No, there is no direct passenger rail service to Lexington.

Are there tolls on this route?

Generally, no, but check for local toll roads.

What is the best time to visit Lexington?

Spring and fall are the best times for horse racing.

Roanoke

Lexington

Driving

Roanoke to Lexington

Updated: 28 May 2026

The drive from Roanoke to Lexington is approximately 350 miles, primarily following I-81 and I-64. This route takes you through the scenic Appalachian Mountains and into the heart of Kentucky. It is a manageable drive that can be completed in about 6 hours. Lexington is known as the Horse Capital of the World and is famous for its horse farms and bourbon distilleries.

Total Distance: 565 km driving distance; 400 km straight-line air distance.

Fastest Way

Driving via I-81 and I-64 is the fastest, taking about 6 hours.

Cheapest Way

Driving is the most cost-effective method, costing roughly $75 in fuel.

Compare Roanoke to Lexington Routes

Driving

Direct

Duration

6 hours

Avg Price

$65-$85 in fuel

Operator

Personal Vehicle

Route

I-81 N to I-64 W.

The route is straightforward but requires attention to speed limits.

Travel Tips

Traffic Awareness
Check for construction on I-64, especially near the Kentucky border.
Fuel Stops
Fill up in Virginia to take advantage of lower fuel prices.
Rest Stops
Use the rest areas along the highway to stretch your legs.
Navigation
Use a reliable GPS to avoid getting lost in rural areas.
Snacks
Bring a cooler with drinks and snacks to save time and money.