The journey from Rogers to St. Louis spans approximately 420 miles via US-412 and US-65. Driving takes roughly 6.5 hours, passing through the scenic Ozark Mountains. Alternatively, regional flights from Northwest Arkansas National Airport (XNA) to St. Louis Lambert International (STL) offer a 1-hour transit. This route connects the growing Northwest Arkansas corridor to the historic Mississippi River hub. Expect varied terrain ranging from rolling hills to flat plains as you cross into Missouri.
Total Distance: 675 km driving distance; 480 km straight-line air distance.
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Direct
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Direct
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|---|---|---|
| Duration | 1 hour 15 mins | 6 hours 30 mins |
| Avg Price | $250-$450 | $60-$90 in fuel |
| Operator | American Airlines | Personal Vehicle |
| Route | XNA to STL | US-412 E to US-65 N, merging onto I-44 E. |
| Tip | Book at least three weeks in advance to secure lower fares on this regional route. | Stop in Springfield, Missouri for a break at the original Bass Pro Shops. |
May and October offer mild temperatures and clear roads for driving through the Ozarks.