The drive from Royston to Memphis is approximately 400 miles, taking about 6 hours. You will travel west on I-20 and then north on I-22 through Alabama and Mississippi. This route is efficient and avoids the worst of the Atlanta traffic if you leave early. It is a straightforward drive across the South.
Total Distance: 640 km driving, 550 km air distance.
Watch for speed traps in small towns along the route.
Spring or Fall for pleasant weather.