Is there a train to Des Moines?

There is no direct passenger train service from Salina to Des Moines.

How long is the drive?

The drive takes about 5 hours and 30 minutes.

There are no major tolls on this route.

What is the best route?

I-35 North is the most direct route.

Yes, it is a major interstate route with frequent services.

Salina

Des Moines

Driving

Salina to Des Moines

Updated: 28 May 2026

The drive from Salina to Des Moines covers approximately 350 miles, primarily via I-70 East and I-35 North. This route takes you through the heart of Kansas and into Iowa, passing through cities like Topeka and Kansas City. The journey typically takes 5 hours and 30 minutes. It is a straightforward drive that connects the plains of Kansas to the agricultural heartland of Iowa.

Total Distance: 565 km driving distance; 500 km straight-line air distance.

Fastest Way

Driving is the most practical and fastest method for this route.

Cheapest Way

Driving is the most economical way to reach Des Moines from Salina.

Compare Salina to Des Moines Routes

Driving

Direct

Duration

5 hours 30 mins

Avg Price

$55-$75 in fuel

Operator

Personal Vehicle

Route

I-70 E to Kansas City, then I-35 N into Des Moines.

Kansas City is a good place to stop for a meal.

Travel Tips

Kansas City Stop
Plan a stop in Kansas City to break up the drive.
Traffic Planning
Avoid rush hour traffic in Kansas City.
Hydration
Keep water in the car for the drive.
Vehicle Check
Ensure your vehicle is in good condition before starting the trip.
Navigation
Use a GPS app to stay updated on traffic conditions.