Driving
Santa Fe to Jackson
Updated: 29 May 2026
The drive from Santa Fe to Jackson covers 420 miles. You will travel north through East Texas and then east across Louisiana into Mississippi. The journey typically takes 6 hours, depending on traffic in the Houston and Shreveport areas. Driving is the only practical mode of transport for this route. Expect a mix of rural highway driving and interstate travel.
Total Distance: 676 km driving distance; 580 km straight-line air distance.
Fastest Way
Driving via US-59 and I-20 takes 6 hours.
Cheapest Way
Driving your own vehicle is the most economical option.
Compare Santa Fe to Jackson Routes
Driving
Direct
Duration
6 hours
Avg Price
$75-$100 in fuel
Operator
Personal Vehicle
Route
US-59 N to I-20 E.
I-20 through Shreveport can be heavy with traffic.
Travel Tips
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TrafficAvoid the I-20/I-55 interchange in Jackson during rush hour.
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FoodStop in Shreveport for a variety of dining options.
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NavigationUse a GPS to navigate the complex highway interchanges in Houston.
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Rest StopsThere are numerous well-maintained rest areas along I-20.
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FuelGas prices are generally lower in Mississippi than in Texas.
Safety Tips
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SpeedingState troopers are active on I-20 across all states.
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WeatherBe prepared for sudden rain in the humid climate.
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Road HazardsWatch for debris from large trucks on the interstate.
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EmergencyKeep your phone charged and have a car charger handy.
People Also Ask
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Is there a train to Jackson?No, there is no passenger rail service to Jackson.
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How long is the drive?It takes about 6 hours.
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What is the best route?US-59 to I-20 is the primary route.
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Is it a flat drive?Yes, the entire route is very flat.
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Are there tolls?No, I-20 is toll-free in this section.
Quick Info
- From Santa Fe, Texas, United States
- To Jackson, Mississippi, United States
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Modes
Best Time to Travel
Spring or Fall for comfortable weather.
Things to Do in Jackson
1
Mississippi State Capitol
Visit the historic capitol building. It is a beautiful example of architecture.
2
Mississippi Museum of Natural Science
Explore exhibits on local wildlife and ecosystems. It is great for families.
3
Jackson Zoological Park
See a variety of animals in a natural setting. It is a popular local attraction.
4
Mississippi Civil Rights Museum
Learn about the history of the civil rights movement. It is a powerful experience.
Tags
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