The drive from Santa Fe to Las Vegas covers 1,500 miles. You will travel west through Texas, New Mexico, and Arizona into Nevada. The journey typically takes 22 hours, depending on traffic in the Houston, Phoenix, and Las Vegas areas. Driving is the only practical mode of transport for this route. Expect a mix of rural highway driving and interstate travel.
Total Distance: 2414 km driving distance; 2100 km straight-line air distance.
I-15 through California can be heavy with traffic.
Spring or Fall for comfortable weather.