The drive from Santa Fe to Los Angeles covers 1,550 miles. You will travel west through Texas, New Mexico, and Arizona into California. The journey typically takes 23 hours, depending on traffic in the Houston, Phoenix, and Los Angeles areas. Driving is the only practical mode of transport for this route. Expect a mix of rural highway driving and interstate travel.
Total Distance: 2494 km driving distance; 2200 km straight-line air distance.
I-10 through Los Angeles can be heavy with traffic.
Spring or Fall for comfortable weather.