Is there a train to Laredo?

No, there is no passenger rail service to Laredo.

How long is the drive?

The drive is approximately 2 hours and 30 minutes.

What is the best route?

I-35 South is the primary highway route.

You can take a bus from San Antonio to Laredo.

Yes, it is a standard highway route.

Seguin

Laredo

Driving

Seguin to Laredo

Updated: 31 May 2026

The trip from Seguin to Laredo is approximately 160 miles, heading southwest through the brush country of South Texas. The most direct route is via I-10 West to I-35 South. This drive typically takes about two and a half hours. Laredo is a major international port of entry on the border with Mexico. It is a hub for trade and logistics, with a unique cultural blend.

Total Distance: 260 km driving distance, 230 km straight-line air distance.

Fastest Way

Driving via I-35 is the fastest method, taking about two and a half hours.

Cheapest Way

Driving your own vehicle is the most practical and cheapest way to travel.

Compare Seguin to Laredo Routes

Driving

Direct

Duration

2 hours 30 mins

Avg Price

$30-$40 in fuel

Operator

Personal Vehicle

Route

I-10 West to I-35 South.

Expect heavy truck traffic on I-35 as you approach the border.

Travel Tips

Truck Traffic
Be patient with heavy truck traffic on I-35 South.
Border Awareness
If you plan to cross the border, ensure you have your passport and necessary documents.
Heat
South Texas can be extremely hot; keep your vehicle's AC in good working order.
Dining
Enjoy authentic Mexican cuisine at local restaurants in Laredo.
Navigation
Use GPS to navigate the city, as the border area can be busy.