The drive from Sewanee to Macon takes you south through Georgia. You will take I-24 East to I-75 South. The total distance is approximately 250 miles. Expect a drive time of about 4 hours. This route is well-traveled and straightforward.
Total Distance: 400 km driving distance, 320 km air distance.
Traffic in Atlanta can be heavy.
Spring for the Cherry Blossom Festival.