The drive from Sewanee to Pensacola takes you south through Alabama and into Florida. You will take I-24 West to I-65 South, then I-10 East. The total distance is approximately 360 miles. Expect a drive time of about 5.5 hours. This route is well-traveled and straightforward.
Total Distance: 580 km driving distance, 460 km air distance.
Traffic in Birmingham and Montgomery can be heavy.
Summer for the beach.