How long is the drive to St. Louis?

It is about 17 hours of driving time.

Is there a direct flight?

Yes, direct flights are sometimes available from LGA to STL.

What is the best time to visit?

Spring and fall are the most comfortable times.

Do I need a car in St. Louis?

A car is helpful for exploring the wider region, but the city has some public transit.

Are there trains to St. Louis?

Yes, Amtrak's Lincoln Service and Texas Eagle lines serve St. Louis.

Smithtown

Saint Louis

Flight Driving

Smithtown to Saint Louis

Updated: 29 May 2026

The journey from Smithtown to St. Louis is approximately 1,000 miles. Driving takes about 16 to 18 hours, typically via I-80 and I-70. Flying from JFK or ISP to St. Louis Lambert International Airport (STL) is much faster, taking about 5 to 6 hours. St. Louis is known for the Gateway Arch and its rich history as the 'Gateway to the West.' This route crosses the Appalachian Mountains and the Midwest plains.

Total Distance: 1,600 km driving distance; 1,450 km straight-line air distance.

Fastest Way

Flying from LGA or JFK is the fastest, taking about 5 hours including airport time.

Cheapest Way

Driving is the most cost-effective for groups.

Compare Smithtown to Saint Louis Routes

	Flight Connecting	Driving Direct
Duration	5 hours	17 hours
Avg Price	$250-$500	$180-$250 in fuel
Operator	Southwest Airlines	Personal Vehicle
Route	LGA or JFK to STL.	I-80 West to I-70 West.
Tip	Check for direct flights from LGA to STL.	Plan for an overnight stop in Pennsylvania or Ohio.

Travel Tips

Weather
St. Louis can have extreme weather; check the forecast before you go.
Transportation
The MetroLink light rail is a convenient way to get around the city.
Dining
Try the local St. Louis-style pizza and toasted ravioli.
Safety
Stick to well-populated areas, especially at night.
Parking
Use parking garages in downtown areas.