Is there a train to Kansas City?

Amtrak serves Kansas City, but there is no direct rail line from St Joseph, MN.

What is the best highway?

I-35 South is the primary and most efficient highway for this route.

This route is generally toll-free through Iowa and Missouri.

How long is the drive?

The drive takes approximately 7 hours and 15 minutes.

Is it safe to drive alone?

Yes, the route is well-traveled and safe during daylight hours.

St Joseph

Kansas City

Driving

St Joseph to Kansas City

Updated: 28 May 2026

The journey from St Joseph, Minnesota to Kansas City, Missouri covers approximately 480 miles. Most travelers prefer driving via I-35 South, which provides a direct path through Des Moines. The drive typically takes about 7 hours depending on traffic in the Twin Cities area. You will pass through diverse landscapes ranging from Minnesota forests to Iowa farmlands. This route is highly efficient for those moving between the Upper Midwest and the heart of the Great Plains.

Total Distance: 772 km driving distance; 680 km straight-line air distance.

Fastest Way

Driving via I-35 South is the fastest way to reach Kansas City from St Joseph.

Cheapest Way

Driving is the most cost-effective method for groups or individuals with a personal vehicle.

Compare St Joseph to Kansas City Routes

Driving

Direct

Duration

7 hours 15 mins

Avg Price

$60-$90 in fuel

Operator

Personal Vehicle

Route

I-35 South through Des Moines and Ames.

Avoid rush hour traffic in Minneapolis to save time.

Travel Tips

Fuel Stops
Des Moines is the perfect midpoint for refueling and grabbing a meal.
Traffic Awareness
Check local traffic reports for the I-35 corridor near Des Moines to avoid construction delays.
Vehicle Check
Ensure your tire pressure is optimal before starting this long-distance drive.
Navigation
Download offline maps as cellular service can be spotty in rural Iowa.
Rest Breaks
Plan for at least two 20-minute breaks to maintain alertness on the highway.

Safety Tips

Winter Driving
Minnesota and Iowa highways can be icy; carry an emergency kit with blankets and salt.
Speed Limits
Strictly adhere to speed limits in small towns along the route to avoid fines.
Wildlife
Be cautious of deer crossings, especially during dawn and dusk hours.
Emergency Prep
Keep a physical road atlas in your glove box for backup navigation.