Like any major city, exercise standard urban precautions, especially at night.

How long is the drive?

The drive takes approximately 4 hours of pure driving time.

Amtrak serves Des Moines, but there is no rail connection from St Louis Park.

What is the best time to visit?

Summer and Fall are the most pleasant times to visit.

Are there direct flights?

No, you will likely have at least one layover in a major hub like Minneapolis.

St Louis Park

Des Moines

Driving

St Louis Park to Des Moines

Updated: 30 May 2026

The journey from St Louis Park, Minnesota to Des Moines, Iowa covers approximately 400 kilometers. Driving is the most practical method, typically utilizing I-35 South. You will transition from the Twin Cities to the capital city of Des Moines.

Total Distance: 400 km driving distance, 380 km straight-line air distance.

Fastest Way

Driving is the fastest, taking about 4 hours.

Cheapest Way

Driving is the most cost-effective for groups of three or more.

Compare St Louis Park to Des Moines Routes

Driving

Direct

Duration

4 hours

Avg Price

$50 - $100 in fuel

Operator

Personal Vehicle

Route

I-35 S.

The drive is straightforward and relatively flat.

Travel Tips

Driving Pace
The drive can be done in one day, but take breaks in the small towns along the way.
Local Food
Try the local cuisine; Des Moines is known for its diverse food scene.
Route Planning
I-35 South is the main artery into Des Moines from the north.
Hydration
Stay hydrated during the long drive, especially when passing through the plains.

Safety Tips

Winter Driving
Avoid driving through the plains during winter storms; road conditions can be treacherous.
Tire Safety
Check your vehicle's tires before the long drive, as the heat can cause blowouts.
Night Driving
Avoid driving through rural areas at night to minimize risks from wildlife.
Emergency Kit
Keep a well-stocked emergency kit in your car for the long cross-country journey.