St. Louis
St. Louis
Tampa
Tampa
Flight Driving

St. Louis to Tampa

Updated: 28 May 2026

The journey from St. Louis to Tampa is approximately 1,700 km. Driving via I-57 and I-75 takes about 16 hours. Flying into Tampa International Airport (TPA) is a popular and efficient choice, with direct flights available. Tampa offers a mix of beautiful beaches, historic districts, and modern attractions.

Total Distance: 1,700 km driving distance; 1,500 km straight-line air distance.
Fastest Way
Flying is significantly faster.
Cheapest Way
Flying is often cheaper than driving.
Compare St. Louis to Tampa Routes
Flight
Direct
Driving
Direct
Duration 2 hours 45 mins 16 hours
Avg Price $180 - $450 $230 in fuel
Operator Southwest Airlines Personal Vehicle
Route STL to TPA. I-57 S to I-24 E to I-75 S.
Tip TPA is consistently ranked as one of the best airports. This is a long drive; plan for an overnight stop.
Travel Tips
  • Airport
    TPA is very easy to navigate.
  • Transport
    Renting a car is recommended for exploring the area.
  • Weather
    Summers are hot and humid; plan accordingly.
  • Sun Protection
    The Florida sun is strong; wear sunscreen.
  • Events
    Check the city calendar for festivals and events.
Safety Tips
  • Traffic
    I-275 can be busy; plan for delays.
  • Emergency
    Keep your phone charged for navigation.
  • Hydration
    Drink plenty of water in the Florida heat.
  • Night Driving
    Be alert for tourists who may be unfamiliar with the roads.
People Also Ask
  • Is it better to fly or drive?
    Flying is usually faster and more cost-effective.
  • How long is the flight?
    Direct flights take about 2.75 hours.
  • Are there direct flights?
    Yes, several airlines offer direct service.
  • What is the best way to get around?
    A rental car is the most convenient option.
  • Is Tampa safe?
    Yes, the tourist areas are generally very safe.
Quick Info
  • From St. Louis, Missouri, United States
  • To Tampa, Florida, United States
  • Modes
Best Time to Travel

Winter and Spring for pleasant weather.

Things to Do in Tampa
1
Busch Gardens
A popular theme park with roller coasters and animal exhibits.
2
The Florida Aquarium
Explore marine life in a beautiful waterfront setting.
3
Ybor City
A historic district known for its Cuban heritage and nightlife.
4
Tampa Riverwalk
A scenic path along the river with access to museums and parks.
Tags
St. Louis to Tampa STL to TPA flights driving to Tampa I-57 route Florida travel Tampa transport St. Louis travel best way to Tampa