The drive from State College to Buffalo is approximately 200 miles, taking about 3.5 to 4 hours. The most direct route is via I-80 West to I-219 North. This journey takes you through the beautiful Allegheny National Forest region of Pennsylvania and into Western New York. It is a popular route for those visiting Niagara Falls or the Buffalo area. Expect scenic, winding roads in the northern part of the trip.
Total Distance: 320 km driving distance; 270 km straight-line air distance.
The drive through the Allegheny National Forest is very scenic.
Spring through Fall for the best weather and access to outdoor activities.