The journey from Syracuse to Binghamton covers approximately 75 miles via Interstate 81 South. This route takes you through the scenic rolling hills of Central New York. Driving is the most efficient method, typically taking about 1 hour and 20 minutes. Bus services are available for those preferring public transit. The route is straightforward and well-maintained throughout the year.
Total Distance: 120 km driving distance; 115 km straight-line air distance.
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Direct
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Direct
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| Duration | 1 hour 45 mins | 1 hour 20 mins |
| Avg Price | $25-$40 | $15-$20 in fuel |
| Operator | OurBus | Personal Vehicle |
| Route | Syracuse Regional Transportation Center to Binghamton University. | I-81 South through Cortland and Whitney Point. |
| Tip | Book online in advance to secure lower fares. | Watch for speed traps near the Cortland exit. |
September and October for peak fall foliage views along the I-81 corridor.