The route from Tulare to St. Louis covers the heart of the country. Flying from Fresno (FAT) to St. Louis Lambert (STL) is the most efficient. Driving involves taking I-40 East and connecting to I-44 East. This route offers a scenic look at the American Midwest.
Total Distance: 3,100 km driving, 2,700 km air.
Southwest often offers competitive rates for this route.
Spring and Fall offer the most pleasant weather.