The route from Tusayan to Mesa covers approximately 360 kilometers, taking you from the Grand Canyon region into the heart of the East Valley. You will travel south on I-17 until reaching the Phoenix area, then transition to the US-60 East to reach Mesa. This journey typically takes 4 hours, though traffic in the Phoenix metropolitan area can significantly impact travel time. The route offers a dramatic descent from the high-altitude forests of Northern Arizona into the sprawling urban landscape of the Sonoran Desert.
Total Distance: 360 km driving distance; 290 km straight-line air distance.
Use the HOV lanes on I-17 if you have multiple passengers.
November to March for pleasant weather in the Mesa area.