The journey from Van Alstyne to Denver is approximately 1,200 kilometers. You will take US-75 South to US-380 West, then merge onto US-287 North all the way to Denver. This route typically takes 12 to 14 hours. It is a long but direct drive through the Texas Panhandle and into Colorado.
Total Distance: 1,200 km driving distance; 1,050 km straight-line air distance.
Expect heavy traffic near the Denver city limits.
Travel mid-week to avoid weekend traffic on US-287.