Waynesboro
Waynesboro
Mesa
Mesa
Driving

Waynesboro to Mesa

Updated: 28 May 2026

The drive from Waynesboro to Mesa is a long journey across the United States. You will take I-81 S to I-40 W, then head south on I-17. The trip covers approximately 3,600 km and takes about 34 hours. This route is a major artery for travelers heading to the Southwest.

Total Distance: Driving distance 3,600 km, Air distance 3,100 km.
Fastest Way
Driving is the fastest option as there are no direct flights from local airports.
Cheapest Way
Driving is the most economical way to reach Mesa from Waynesboro.
Compare Waynesboro to Mesa Routes
Driving
Direct
Duration
34 hours
Avg Price
$400 - $500 in fuel
Operator
Personal Vehicle
Route
I-81 S to I-40 W to I-17 S.

This is a long drive; plan for at least two overnight stays.

Travel Tips
  • Traffic
    Expect heavy traffic in Mesa during rush hour.
  • Parking
    Use the parking garages in downtown Mesa for easy access.
  • Food
    Try the local Sonoran-style Mexican food.
  • Walking
    The downtown area is walkable, but you will need a car for other attractions.
  • Events
    Check the schedule for events at the Mesa Arts Center.
Safety Tips
  • Highway Safety
    Stay alert for construction zones on I-17.
  • Night Driving
    Avoid long stretches of night driving if you are fatigued.
  • Emergency
    Keep an emergency kit in your car for long-distance travel.
  • General Safety
    Stick to well-lit areas when walking downtown at night.
People Also Ask
  • Is the drive safe?
    Yes, the route is well-traveled and safe.
  • Are there tolls?
    Generally, this route is toll-free.
  • What is the best route?
    I-81 S to I-40 W to I-17 S is the most direct route.
  • Is Mesa walkable?
    The downtown area is walkable, but you will need a car for other attractions.
  • What is the best time to visit?
    Winter and spring offer the best weather for outdoor activities.
Quick Info
  • From Waynesboro, Virginia, United States
  • To Mesa, Arizona, United States
  • Modes
Best Time to Travel

Winter or Spring for pleasant weather.

Things to Do in Mesa
1
Arizona Museum of Natural History
Explore the history of the region, including dinosaur exhibits.
2
Mesa Arts Center
Visit this beautiful center for art, music, and theater.
3
Usery Mountain Regional Park
Enjoy hiking and biking in this beautiful desert park.
4
Superstition Mountains
Take a day trip to these iconic mountains for hiking and scenic views.
Tags
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