Is there a bus to Las Vegas?

Yes, Greyhound offers service from St. Louis to Las Vegas with transfers.

How long is the drive?

The drive is approximately 25 hours.

What is the best route?

I-70 West to I-15 South is the most direct path.

Yes, there are direct flights from St. Louis (STL) to Las Vegas (LAS).

Las Vegas is generally safe, but stick to well-lit, populated areas in the tourist districts.

Wentzville

Las Vegas

Driving

Wentzville to Las Vegas

Updated: 28 May 2026

The drive from Wentzville to Las Vegas is a massive 1,700-mile cross-country journey. You will head west through Missouri, Kansas, Colorado, and Utah before entering Nevada. The primary route involves taking I-70 West to I-15 South. Expect a driving time of approximately 25 hours. This is a major long-distance trip that requires careful planning and multiple overnight stops.

Total Distance: 2,735 km driving distance; 2,350 km straight-line air distance.

Fastest Way

Driving via I-70 and I-15 is the fastest route, taking 25 hours.

Cheapest Way

Driving your own vehicle is the most economical choice at roughly $300 in fuel.

Compare Wentzville to Las Vegas Routes

Driving

Direct

Duration

25 hours

Avg Price

$270-$380

Operator

Personal Vehicle

Route

I-70 W to I-15 S through Denver, Salt Lake City, and St. George.

Mountain passes in Colorado and Utah can be challenging; check weather conditions.

Travel Tips

Traffic
Las Vegas traffic can be heavy; plan your travel to avoid peak rush hours.
Rest Stops
Salt Lake City, Utah, is a good place to stop for a meal and a break.
Weather
Las Vegas is extremely hot in the summer; stay hydrated and wear sunscreen.
Tolls
There are few tolls on this route, but be aware of local express lanes in major cities.
Navigation
Use a GPS with real-time traffic updates to navigate the complex highway systems in major cities.

Safety Tips

Fatigue
This is a very long drive; plan for at least two overnight stops to stay safe.
Vehicle Check
Check your tires and cooling system, as the heat and distance are demanding on vehicles.
Emergency Kit
Carry extra water and a first-aid kit, as some stretches of I-15 are quite remote.
Speeding
Utah and Nevada state police are very active on the interstates; watch your speed.