Is there a bus to Minneapolis?

Yes, Jefferson Lines and Greyhound offer service to Minneapolis.

How long is the drive?

The drive is approximately 8.5 hours.

What is the best route?

Taking I-35 North is the most direct and common route.

Yes, there are direct flights from St. Louis (STL) to Minneapolis (MSP).

Minneapolis is generally safe, but standard urban precautions should be taken.

Wentzville

Minneapolis

Driving

Wentzville to Minneapolis

Updated: 28 May 2026

The journey from Wentzville to Minneapolis covers approximately 550 miles, primarily following I-70 East to I-55 North, then connecting to I-35 North. You will pass through the scenic landscapes of Iowa and Southern Minnesota. The drive takes about 8.5 hours under normal conditions. This route is a major corridor for travelers heading to the Upper Midwest. Expect varied terrain as you move from the Missouri plains to the lakes of Minnesota.

Total Distance: 885 km driving distance; 780 km straight-line air distance.

Fastest Way

Driving via I-35 is the fastest route, taking 8.5 hours.

Cheapest Way

Driving your own vehicle is the most cost-effective method at roughly $80 in fuel.

Compare Wentzville to Minneapolis Routes

Driving

Direct

Duration

8.5 hours

Avg Price

$70-$110

Operator

Personal Vehicle

Route

I-70 E to I-55 N, then I-35 N through Des Moines.

Use the I-35 corridor through Iowa for the most efficient path.

Travel Tips

Traffic
Avoid the Minneapolis downtown area during morning and evening rush hours.
Rest Stops
Albert Lea, Minnesota, is a convenient stop for fuel and food before the final stretch.
Weather
Be prepared for rapid weather changes; check the forecast for the entire I-35 corridor.
Parking
Use public transit or ride-sharing apps to avoid expensive downtown parking fees.
Navigation
Keep a physical map as a backup, as cell service can be intermittent in rural Iowa.

Safety Tips

Winter Driving
Minnesota winters are harsh; ensure your vehicle is equipped for snow and ice.
Fatigue
This is a long drive; plan for at least two major rest stops to avoid driver fatigue.
Wildlife
Be vigilant for deer, especially when driving through wooded areas in Minnesota.
Emergency Kit
Carry a winter emergency kit including blankets, a shovel, and sand if traveling in colder months.