Wentzville
Wentzville
New Orleans
New Orleans
Driving

Wentzville to New Orleans

Updated: 28 May 2026

The drive from Wentzville to New Orleans covers approximately 750 miles, taking you south through Missouri, Tennessee, Mississippi, and Louisiana. You will primarily follow I-55 South all the way to the Gulf Coast. Expect a driving time of approximately 11 hours. This is a straightforward route that takes you through the heart of the Mississippi River valley.

Total Distance: 1,207 km driving distance; 1,050 km straight-line air distance.
Fastest Way
Driving via I-55 South is the fastest route, taking 11 hours.
Cheapest Way
Driving your own vehicle is the most economical choice at roughly $110 in fuel.
Compare Wentzville to New Orleans Routes
Driving
Direct
Duration
11 hours
Avg Price
$100-$150
Operator
Personal Vehicle
Route
I-55 S through Memphis and Jackson to New Orleans.

Memphis traffic can be heavy; plan your transit accordingly.

Travel Tips
  • Traffic
    New Orleans traffic can be heavy; use a navigation app to avoid congestion.
  • Rest Stops
    Memphis, Tennessee, is a perfect midpoint for a meal and a break.
  • Weather
    New Orleans is humid; pack light, breathable clothing for your visit.
  • Parking
    Downtown New Orleans parking can be pricey; look for public lots or hotel parking deals.
  • Navigation
    Use a GPS with real-time traffic updates to navigate the city's unique street layout.
Safety Tips
  • Fatigue
    This is a long drive; take regular breaks to stay alert on the highway.
  • Vehicle Check
    Check your tires and fluids before starting this long drive through multiple states.
  • Emergency Kit
    Carry extra water and a first-aid kit, as some stretches of I-55 are quite remote.
  • Speeding
    Mississippi and Louisiana state police are very active on the interstates; watch your speed.
People Also Ask
  • Is there a bus to New Orleans?
    Yes, Greyhound offers service from St. Louis to New Orleans with transfers.
  • How long is the drive?
    The drive is approximately 11 hours.
  • What is the best route?
    I-55 South is the most direct path.
  • Are there flights?
    Yes, there are direct flights from St. Louis (STL) to New Orleans (MSY).
  • Is New Orleans safe?
    New Orleans is generally safe, but stick to well-lit, populated areas in the tourist districts.
Quick Info
  • From Wentzville, Missouri, United States
  • To New Orleans, Louisiana, United States
  • Modes
Best Time to Travel

February to May or October to December for mild weather and cultural festivals.

Things to Do in New Orleans
1
French Quarter
The historic heart of the city, famous for its architecture, jazz clubs, and restaurants.
2
Garden District
Known for its beautiful historic mansions and oak-lined streets.
3
National WWII Museum
A world-class museum dedicated to the history of the Second World War.
4
Jackson Square
A historic park in the French Quarter, featuring street performers and artists.
Tags
Wentzville to New Orleans drive I-55 South route driving to New Orleans New Orleans travel guide Missouri to Louisiana road trip Wentzville to New Orleans distance best way to New Orleans Louisiana travel