Wentzville
Wentzville
Orlando
Orlando
Driving

Wentzville to Orlando

Updated: 28 May 2026

The drive from Wentzville to Orlando is a major cross-country trek covering 1,100 miles. You will head south and east through Kentucky, Tennessee, and Georgia before entering Florida. The primary route involves taking I-64 East to I-75 South. Expect a driving time of approximately 17 hours. This is a popular route for families heading to the theme parks, so plan for multiple overnight stops.

Total Distance: 1,770 km driving distance; 1,500 km straight-line air distance.
Fastest Way
Driving via I-64 and I-75 is the fastest route, taking 17 hours.
Cheapest Way
Driving your own vehicle is the most economical choice at roughly $180 in fuel.
Compare Wentzville to Orlando Routes
Driving
Direct
Duration
17 hours
Avg Price
$160-$240
Operator
Personal Vehicle
Route
I-64 E to I-75 S through Nashville, Atlanta, and Gainesville.

Atlanta traffic is a major bottleneck; try to pass through at night or mid-day.

Travel Tips
  • Traffic
    Atlanta and Orlando traffic can be very heavy; plan your arrival times carefully.
  • Rest Stops
    Atlanta, Georgia, is a good place to stop, but consider staying in a suburb to avoid downtown traffic.
  • Weather
    Florida is hot and humid; stay hydrated and wear sunscreen.
  • Tolls
    Florida has many toll roads; consider getting a SunPass for easier travel.
  • Navigation
    Use a GPS with real-time traffic updates to navigate the complex highway systems in major cities.
Safety Tips
  • Fatigue
    This is a very long drive; plan for at least one overnight stop to stay safe.
  • Vehicle Check
    Check your tires and cooling system, as the heat and distance are demanding on vehicles.
  • Emergency Kit
    Carry extra water and a first-aid kit, as some stretches of I-75 are quite remote.
  • Speeding
    Georgia and Florida state police are very active on the interstates; watch your speed.
People Also Ask
  • Is there a bus to Orlando?
    Yes, Greyhound offers service from St. Louis to Orlando with transfers.
  • How long is the drive?
    The drive is approximately 17 hours.
  • What is the best route?
    I-64 East to I-75 South is the most direct path.
  • Are there flights?
    Yes, there are direct flights from St. Louis (STL) to Orlando (MCO).
  • Is Orlando safe?
    Orlando is generally safe, but stick to well-lit, populated areas in the tourist districts.
Quick Info
  • From Wentzville, Missouri, United States
  • To Orlando, Florida, United States
  • Modes
Best Time to Travel

March to May or September to November for pleasant weather and fewer crowds.

Things to Do in Orlando
1
Walt Disney World
The world's most famous theme park resort, featuring four major parks and two water parks.
2
Universal Orlando
Home to the Wizarding World of Harry Potter and thrilling movie-themed rides.
3
SeaWorld Orlando
A marine-themed park featuring shows, exhibits, and high-speed roller coasters.
4
ICON Park
An entertainment complex featuring a giant observation wheel and various dining options.
Tags
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