The drive from Wichita Falls to San Antonio covers approximately 480 kilometers and takes about 5 hours. You will travel south on US-287 to the Dallas-Fort Worth area, then take I-35 S all the way to San Antonio. This route takes you through the heart of Texas. Be prepared for heavy traffic in the DFW and San Antonio metro areas. Plan your stops in advance to make the journey more comfortable.
Total Distance: Driving distance 480 km, Air distance 430 km.
I-35 can be very congested; check traffic apps before departing.
Spring or Autumn to avoid the hot Texas summer.