The drive from Wichita Falls to Santa Fe is a 950-kilometer journey through the high plains and into the mountains of New Mexico. You will head north on US-287 to Amarillo, then take US-87 and I-25 North to Santa Fe. This route offers beautiful desert and mountain scenery. Expect significant elevation changes. Plan for about 10 hours of driving time.
Total Distance: 950 km driving distance; 850 km straight-line air distance.
Amarillo is a great place to stop for a meal and fuel.
May to October for pleasant mountain weather.