The drive from Williamsport to Harrisburg is a straightforward 75-mile journey heading north on I-81. You will cross the state line into Pennsylvania, passing through Hagerstown and Chambersburg. The trip typically takes about 80 minutes under normal traffic conditions. This route is scenic, passing through the Cumberland Valley. It is a popular route for commuters and those visiting the Pennsylvania State Capitol.
Total Distance: 120 km driving distance; 105 km straight-line air distance.
I-81 is heavily used by freight trucks; maintain a safe distance and be patient.
Late spring or early fall offers the best driving conditions through the valley.