How long is the drive?

It is about 4 hours from Woodbury.

No, there is no passenger rail service to Des Moines.

What is the best route?

I-35 South is the only major highway route.

Is it a good day trip?

It is a bit long for a day trip, but perfect for a weekend.

Woodbury

Des Moines

Driving

Woodbury to Des Moines

Updated: 28 May 2026

The drive from Woodbury to Des Moines is a 250-mile trip south through the heart of the Midwest. You will take I-494 to I-35 South, which takes you directly into Iowa's capital city. The journey typically takes 4 hours. Des Moines is known for its vibrant downtown, the gold-domed State Capitol, and the annual Iowa State Fair.

Total Distance: 400 km driving distance; 360 km straight-line air distance.

Fastest Way

Driving is the fastest method, taking 4 hours.

Cheapest Way

Driving your own vehicle is the most cost-effective way to reach Des Moines.

Compare Woodbury to Des Moines Routes

Driving

Direct

Duration

4 hours

Avg Price

$40-$60 in fuel

Operator

Personal Vehicle

Route

I-35 South

The route is very straightforward and passes through Albert Lea.

Travel Tips

Parking
Downtown Des Moines has many affordable parking ramps.
Skywalk System
Use the extensive skywalk system to navigate downtown during cold or rainy weather.
Dining
Try the local pork tenderloin sandwiches, a classic Iowa dish.
Events
Check the city calendar for events at the Wells Fargo Arena.
Walking
The downtown area is very compact and easy to walk.

Safety Tips

Driving
I-35 can be busy with truck traffic; maintain a safe following distance.
Night Safety
Stick to well-lit areas in the downtown core at night.
Emergency
Dial 911 for any urgent assistance.
Weather
Iowa can have severe thunderstorms in summer; monitor local weather alerts.