The drive from Alexandria to Little Rock covers approximately 280 miles through the scenic landscapes of Louisiana and Arkansas. You will head north on US-165 and then transition to US-65, which runs parallel to the Mississippi River. This route takes about 4 hours and 30 minutes. You will pass through rural towns and agricultural areas, offering a glimpse into the heart of the Delta region.
Total Distance: 450 km driving distance; 380 km straight-line air distance.
Stop in Pine Bluff for a quick break and local food.
Spring and Fall are best for mild weather and beautiful scenery.