Driving
Altoona to Rochester
Updated: 28 May 2026
The drive from Altoona to Rochester is approximately 180 kilometers, following US-53 South and US-14 West. This route takes you through the scenic driftless region and across the Mississippi River. The journey takes about 2 hours. It is a common route for medical travelers and visitors to the Mayo Clinic.
Total Distance: 180 km driving, 160 km air distance.
Fastest Way
Driving via US-53 and US-14 is the fastest at 2 hours.
Cheapest Way
Driving is the most economical option.
Compare Altoona to Rochester Routes
Driving
Direct
Duration
2 hours
Avg Price
$25-$35 in fuel
Operator
Personal Vehicle
Route
US-53 South to US-14 West.
The drive across the river valley is very scenic.
Travel Tips
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TrafficTraffic is generally light, except near the medical campus.
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ParkingUse the parking ramps near the Mayo Clinic.
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DiningExplore the diverse restaurant scene in downtown Rochester.
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NavigationThe route is well-marked.
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WeatherBe prepared for cold winters.
Safety Tips
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DrivingStay alert on the highway, especially at night.
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WildlifeWatch for deer in rural areas.
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Road ConditionsCheck for winter road reports.
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EmergencyKeep a basic emergency kit in your vehicle.
People Also Ask
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How long is the drive?Approximately 2 hours.
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Are there tolls?No, there are no tolls on this route.
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Is it a scenic drive?Yes, the driftless area is beautiful.
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What is the best time to visit?Spring and summer.
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Is there public transport?No, driving is the only practical option.
Quick Info
- From Altoona, Wisconsin, United States
- To Rochester, Minnesota, United States
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Modes
Best Time to Travel
Spring and summer for pleasant weather.
Things to Do in Rochester
1
Mayo Clinic
A world-renowned medical center with beautiful architecture and public art.
2
Quarry Hill Nature Center
Features hiking trails, a pond, and a fossil dig site.
3
Silver Lake Park
A great place for walking, biking, and enjoying the outdoors.
4
Rochester Art Center
Features contemporary art exhibits and community programs.
Tags
Altoona to Rochester drive
US-53 route
Rochester travel guide
Mayo Clinic trip
Wisconsin to Minnesota
fastest way to Rochester
driving distance Altoona to Rochester
Rochester transport tips
