Altoona
Altoona
St. Louis
St. Louis
Driving

Altoona to St. Louis

Updated: 28 May 2026

The drive from Altoona to St. Louis covers 500 miles, taking you south through Illinois. You will primarily use I-90 and I-55. The journey takes approximately 8 hours. St. Louis is famous for the Gateway Arch and its vibrant blues music scene. This route is relatively flat and easy to navigate.

Total Distance: 800 km driving, 680 km air.
Fastest Way
Driving is the fastest method as there are no direct flights.
Cheapest Way
Driving is the most cost-effective way to reach St. Louis.
Compare Altoona to St. Louis Routes
Driving
Direct
Duration
8 hours
Avg Price
$100-$160
Operator
Personal Vehicle
Route
I-90 E to I-55 S through Chicago.

Consider taking the I-355 bypass to avoid Chicago traffic.

Travel Tips
  • Bypass Chicago
    Use the I-355 tollway to save time during peak hours.
  • Parking
    Use the Gateway Arch parking garage for convenient access to the monument.
  • Dining
    Try St. Louis-style pizza and toasted ravioli at local restaurants.
  • Navigation
    Use real-time traffic apps to monitor construction on I-55.
  • Weather
    Summers can be very humid; plan indoor activities accordingly.
Safety Tips
  • Vehicle Safety
    Check your coolant levels before driving in the summer heat.
  • Night Driving
    Be alert for wildlife on rural roads in Illinois.
  • Emergency
    Keep a first-aid kit in your vehicle.
  • Urban Safety
    Stay in well-lit areas when visiting downtown at night.
People Also Ask
  • Is there a train?
    No direct train service exists from Altoona to St. Louis.
  • How long is the drive?
    The drive takes about 8 hours.
  • Are there tolls?
    Yes, expect tolls on the I-355 bypass near Chicago.
  • What is the best route?
    I-90 to I-55 is the most direct highway.
  • Is St. Louis walkable?
    Some areas are walkable, but a car is recommended for most attractions.
Quick Info
  • From Altoona, Wisconsin, United States
  • To St. Louis, Missouri, United States
  • Modes
Best Time to Travel

April to May or September to October for mild weather.

Things to Do in St. Louis
1
Gateway Arch
Take a tram to the top of this iconic monument for views of the city.
2
Forest Park
Explore one of the largest urban parks in the US, home to the zoo and museums.
3
City Museum
Experience this unique, interactive playground built from repurposed industrial materials.
4
Anheuser-Busch Brewery
Take a tour of the historic brewery and learn about the city's beer heritage.
Tags
Altoona to St. Louis drive distance Altoona to St. Louis I-90 to I-55 route Wisconsin to Missouri travel best way to St. Louis road trip Wisconsin to Missouri St. Louis travel tips Altoona travel