The drive from Berwyn to Des Moines is approximately 550 kilometers. You will head west on I-88 and then merge onto I-80 W through Iowa. The journey typically takes 5.5 to 6 hours. This route takes you across the Mississippi River and through the heart of the Midwest. It is a straightforward drive across flat plains.
Total Distance: 550 km driving, 480 km air distance.
Stop in the Quad Cities for a meal along the river.
Late spring and early autumn offer the most pleasant weather.