Buffalo
Buffalo
Baltimore
Baltimore
Train Driving

Buffalo to Baltimore

Updated: 28 May 2026

The distance from Buffalo to Baltimore is approximately 600 kilometers. Driving takes about 6 hours via I-81 South. Amtrak offers train service, though it often requires a transfer. Baltimore is known for its historic Inner Harbor and seafood.

Total Distance: 600 km driving, 450 km air distance.
Fastest Way
Driving is the fastest option.
Cheapest Way
Driving is the most cost-effective.
Compare Buffalo to Baltimore Routes
Train
Connecting
Driving
Direct
Duration 9 hours 6 hours
Avg Price $100-$200 $70-$100 in fuel
Operator Amtrak Personal Vehicle
Route Buffalo-Depew Station to Baltimore Penn Station. I-81 S.
Tip Relaxing way to travel. Scenic route through the mountains.
Travel Tips
  • Traffic
    Baltimore traffic can be heavy.
  • Weather
    Winters can be cold.
  • Transport
    Use the light rail.
  • Booking
    Book train tickets early.
  • Food
    Try the crab cakes.
Safety Tips
  • Driving
    Stay alert.
  • City Safety
    Stay in tourist areas.
  • Emergency
    Keep a phone charger.
  • Awareness
    Be aware of surroundings.
People Also Ask
  • How long is the train?
    9-10 hours.
  • Is Baltimore safe?
    Yes, in tourist areas.
  • What is the best time to visit?
    Spring.
  • Are there direct trains?
    No.
  • Is it walkable?
    Yes, in the Inner Harbor.
Quick Info
  • From Buffalo, New York, United States
  • To Baltimore, Maryland, United States
  • Modes
Best Time to Travel

Spring or Fall for pleasant weather.

Things to Do in Baltimore
1
Inner Harbor
Historic waterfront with shops and restaurants.
2
National Aquarium
World-class aquarium.
3
Fort McHenry
Historic site of the Star-Spangled Banner.
4
Fells Point
Historic neighborhood with nightlife.
Tags
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