Driving
Burlingame to San Luis Obispo
Updated: 28 May 2026
The most practical way to travel from Burlingame to San Luis Obispo is by driving via US-101 S. The journey takes approximately 3 hours and 30 minutes. San Luis Obispo is a charming city known for its historic mission, vibrant downtown, and proximity to the beautiful Central Coast beaches.
Total Distance: 320 km driving distance; 280 km air distance.
Fastest Way
Driving via US-101 S.
Cheapest Way
Driving your own vehicle.
Compare Burlingame to San Luis Obispo Routes
Driving
Direct
Duration
3 hours 30 mins
Avg Price
$40 - $60 in fuel
Operator
Personal Vehicle
Route
US-101 S
The drive through the Central Coast is very scenic.
Travel Tips
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WeatherThe weather is mild year-round; bring layers.
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DiningEnjoy the local food scene and farmers market.
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TransportA car is recommended for exploring the area.
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EventsThe Thursday night farmers market is a major local event.
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NavigationUse a map app to find the best routes.
Safety Tips
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DrivingBe cautious on winding roads in the area.
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Personal SafetySan Luis Obispo is safe, but use standard precautions.
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Beach SafetyAlways swim near lifeguard stations.
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NavigationStay alert on the busy US-101 highway.
People Also Ask
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Is San Luis Obispo walkable?Yes, the downtown area is very walkable.
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Are there trains?Yes, the Amtrak Coast Starlight serves the city.
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What is the best time to visit?Spring and Fall are the most pleasant.
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Is the drive difficult?It is straightforward and scenic.
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What is San Luis Obispo famous for?Mission, downtown, and nature.
Quick Info
- From Burlingame, California, United States
- To San Luis Obispo, California, United States
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Modes
Best Time to Travel
March to May or September to November for mild weather.
Things to Do in San Luis Obispo
1
Mission San Luis Obispo de Tolosa
A historic mission founded in 1772 with beautiful grounds.
2
Bubblegum Alley
A unique and quirky local landmark in downtown.
3
Bishop Peak
A popular hiking trail with panoramic views of the city.
4
Downtown SLO
A vibrant area with shops, restaurants, and a weekly farmers market.
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