The drive from Mammoth Lakes to San Luis Obispo is approximately 600 kilometers, taking you through the Eastern Sierra and across the mountains to the Central Coast. The journey takes about 8 hours. A private vehicle is the most practical mode of transport for this route.
Total Distance: 600 km driving distance; 420 km straight-line air distance.
CA-58 is a long, remote stretch; ensure your vehicle is in good condition.
Spring and Fall for pleasant coastal weather.