The drive from Mammoth Lakes to Palmdale is approximately 365 kilometers, following the same path as the Lancaster route via US-395 and CA-14. The journey takes about 4 hours and 15 minutes. Palmdale is a major hub in the Antelope Valley, known for its aerospace industry. A private vehicle is the only practical way to make this trip.
Total Distance: 365 km driving distance; 315 km straight-line air distance.
Palmdale traffic can be heavy during rush hour; plan your arrival accordingly.
Spring for pleasant temperatures and desert wildflowers.