No, there is no direct passenger rail service.

What is the best highway?

I-40 West is the primary route.

Like any major city, stay aware of your surroundings.

Cashiers

Memphis

Driving

Cashiers to Memphis

Updated: 28 May 2026

The journey from Cashiers to Memphis covers approximately 450 miles across the state of Tennessee. You will head west through the Great Smoky Mountains, eventually connecting to I-40 West. The drive typically takes 7 hours. This route offers a transition from the high-altitude mountains to the Mississippi River delta. It is a popular route for those looking to experience Southern music history.

Total Distance: 724 km driving distance, 600 km straight-line air distance.

Fastest Way

Driving via I-40 is the fastest method, taking 7 hours.

Cheapest Way

Driving your own vehicle is the most cost-effective way to travel.

Compare Cashiers to Memphis Routes

Driving

Direct

Duration

7 hours

Avg Price

$70-$95 in fuel

Operator

Personal Vehicle

Route

US-64 to I-40 W

Expect heavy traffic near Nashville on I-40.

Travel Tips

Nashville Traffic
Plan to pass through Nashville outside of peak morning and evening hours.
Music
Create a playlist of Memphis blues to set the mood for your arrival.
Dining
Try the local BBQ in Memphis; it is world-famous.
Parking
Use parking garages downtown for safety and convenience.
Planning
Book your Graceland tickets in advance to avoid long lines.

Safety Tips

Urban Safety
Stay in well-lit, populated areas when exploring downtown at night.
Vehicle Security
Do not leave valuables in your car while parked in public lots.
Road Safety
Be cautious of heavy truck traffic on I-40.
Weather
Monitor weather reports for potential storms in the Tennessee Valley.